Benita S Katzenellenbogen Selected Research

Estrogen Receptor alpha

1/2021	Estrogen receptor gets a grip on RNA.
8/2020	Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers.
1/2017	Non-nuclear estrogen receptor alpha activation in endothelium reduces cardiac ischemia-reperfusion injury in mice.
2/2016	Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
11/2015	Protective Hematopoietic Effect of Estrogens in a Mouse Model of Thrombosis: Respective Roles of Nuclear Versus Membrane Estrogen Receptor α.
10/2015	The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.
10/2011	The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells.
7/2010	Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.
4/2010	Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs).
4/2009	Estrogen receptor alpha represses transcription of early target genes via p300 and CtBP1.

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Benita S Katzenellenbogen Research Topics

Disease

68	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2002
39	Neoplasms (Cancer) 01/2022 - 02/2004
11	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2005
4	Triple Negative Breast Neoplasms 12/2021 - 01/2017
4	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 06/2005
3	Obesity 09/2021 - 08/2007
3	Inflammation (Inflammations) 09/2021 - 01/2015
3	Endometriosis 02/2016 - 12/2014
3	Body Weight (Weight, Body) 02/2016 - 11/2002
3	Weight Gain 02/2016 - 11/2002
3	Carcinogenesis 09/2014 - 11/2006
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2021 - 12/2018
2	Fatty Liver 09/2021 - 02/2016
2	Endometrial Neoplasms (Endometrial Cancer) 09/2021 - 07/2010
2	Insulin Resistance 12/2018 - 10/2016
2	Infarction (Infarctions) 11/2018 - 01/2017
2	Carcinoma (Carcinomatosis) 01/2017 - 04/2005
2	Pelvic Pain 02/2016 - 01/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2021
1	Cognitive Dysfunction 12/2018
1	Neuroinflammatory Diseases 11/2018
1	Stroke (Strokes) 11/2018
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 11/2018
1	Hypertension (High Blood Pressure) 01/2018
1	Atherosclerotic Plaque (Atheroma) 01/2018
1	Confusion (Bewilderment) 01/2017
1	Reperfusion Injury 01/2017
1	Disease Progression 01/2017

Drug/Important Bio-Agent (IBA)

52	Estrogen ReceptorsIBA 01/2022 - 06/2003
41	Estrogens (Estrogen)FDA Link 09/2021 - 02/2003
22	Hormones (Hormone)IBA 01/2019 - 02/2003
18	Estrogen Receptor alphaIBA 01/2021 - 07/2004
18	Estradiol (Delestrogen)FDA LinkGeneric 11/2018 - 10/2003
17	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2004
12	LigandsIBA 01/2021 - 02/2004
11	Transcription Factors (Transcription Factor)IBA 12/2021 - 06/2003
9	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021 - 02/2003
8	Estrogen Receptor betaIBA 01/2021 - 07/2004
8	Tamoxifen FDA LinkGeneric 09/2014 - 02/2004
7	Estrogen Receptor Modulators (Antiestrogen)IBA 06/2020 - 06/2003
7	ChromatinIBA 09/2014 - 06/2007
5	Fulvestrant (Faslodex)FDA Link 01/2022 - 02/2004
4	EnzymesIBA 01/2022 - 05/2005
4	AndrogensIBA 01/2018 - 06/2005
4	Raloxifene Hydrochloride (Evista)FDA Link 12/2008 - 02/2004
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 10/2016
3	Pharmaceutical PreparationsIBA 12/2018 - 02/2003
3	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 06/2005
3	GenisteinIBA 12/2016 - 05/2008
3	Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA 09/2014 - 01/2011
3	Phosphotransferases (Kinase)IBA 05/2014 - 09/2009
3	Selective Estrogen Receptor Modulators (SERM)IBA 12/2008 - 02/2004
3	SteroidsIBA 08/2006 - 04/2005
3	Messenger RNA (mRNA)IBA 09/2005 - 03/2002
2	CollagenIBA 09/2021 - 11/2015
2	(S)- 5- (4- hydroxy- 3,5- dimethyl- phenyl)- indan- 1- olIBA 09/2021 - 11/2018
2	SurvivinIBA 01/2021 - 06/2011
2	Cadherins (E-Cadherin)IBA 01/2021 - 06/2005
2	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 09/2020 - 09/2014
2	Forkhead Box Protein M1IBA 01/2019 - 09/2014
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2017 - 02/2013
2	EquolIBA 12/2016 - 11/2013
2	BESIBA 12/2016 - 11/2013
2	daidzeinIBA 12/2016 - 11/2013
2	LipidsIBA 02/2016 - 08/2007
2	ProhibitinsIBA 02/2016 - 02/2008
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2009 - 08/2008
2	Small Interfering RNA (siRNA)IBA 05/2008 - 06/2005
2	Co-Repressor ProteinsIBA 02/2008 - 09/2005
1	GlycogenIBA 01/2022
1	HydrogelsIBA 01/2022
1	Estrogen Receptor AntagonistsIBA 01/2022
1	Lapatinib (GW572016)FDA Link 12/2021
1	LeptinIBA 09/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 09/2021
1	Glutathione (Reduced Glutathione)IBA 09/2021
1	RNA IsoformsIBA 01/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2021
1	CystatinsIBA 01/2021
1	Exportin 1 ProteinIBA 08/2020
1	selinexorIBA 08/2020
1	LuciferasesIBA 06/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2019
1	xanthohumolIBA 12/2018
1	FlavonoidsIBA 12/2018
1	Angiotensin IIIBA 01/2018
1	EstetrolIBA 01/2018
1	histone H3 trimethyl Lys4IBA 01/2017
1	acrylic acid (acrylate)IBA 01/2017
1	AntibodiesIBA 01/2017
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2017
1	Histones (Histone)IBA 01/2017
1	Indicators and Reagents (Reagents)IBA 01/2017
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2017
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 12/2016
1	Apolipoproteins E (ApoE)IBA 10/2016

Therapy/Procedure

27	Therapeutics 01/2022 - 02/2003
2	Hormone Replacement Therapy (Therapy, Hormone Replacement) 09/2021 - 05/2016
2	Ovariectomy (Oophorectomy) 02/2016 - 11/2002